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1.
Rev. chil. obstet. ginecol. (En línea) ; 88(5): 329-334, oct. 2023. ilus
Article in Spanish | LILACS | ID: biblio-1530021

ABSTRACT

Introducción: El embarazo ectópico intersticial es una forma de presentación poco frecuente, con una incidencia del 2-4% de los embarazos ectópicos; sin embargo, a pesar de su baja incidencia la mortalidad es cinco veces mayor, impactando en las cifras de mortalidad materna y representando en torno al 10-15% de los casos. Objetivo: Presentar un caso de embarazo ectópico intersticial, cuya ocurrencia es poco frecuente, así como el abordaje satisfactorio del manejo médico con mifepristona y metotrexato. Caso clínico: Mujer de 28 años con antecedente de resección tubárica por quiste paraovárico derecho, quien acudió a urgencias por hallazgo en ecografía obstétrica de sospecha de embarazo intersticial izquierdo y se le administró manejo farmacológico con dosis de metotrexato y mifepristona, con éxito. Conclusiones: El manejo médico con metotrexato y mifepristona para el embarazo ectópico intersticial parece ser una elección eficaz en los casos con estabilidad hemodinámica y deseo de conservación de la fertilidad.


Background: Interstitial ectopic pregnancy represents a rare form of presentation, with an incidence of 2-4% of all ectopic pregnancies. However, despite its low incidence, it is associated with a five-fold increase in mortality, significantly impacting maternal mortality rates, accounting for approximately 10-15% of cases. Objective: To present a case of interstitial ectopic pregnancy, which is a rare occurrence, as well as the successful medical management approach with mifepristone and methotrexate. Case report: A 28-year-old women with a history of right paraovarian cyst tubal resection presented to the emergency department due to suspected left interstitial pregnancy identified on obstetric ultrasound. The patient was successfully managed with pharmacological treatment using doses of methotrexate and mifepristone. Conclusions: Medical management with methotrexate and mifepristone for interstitial ectopic pregnancy appears to be an effective choice in cases with hemodynamic stability and a desire for fertility preservation.


Subject(s)
Humans , Female , Pregnancy , Adult , Mifepristone/therapeutic use , Methotrexate/therapeutic use , Pregnancy, Interstitial/drug therapy , Pregnancy, Ectopic , Ultrasonography , Fertility Preservation , Pregnancy, Interstitial/diagnostic imaging
2.
Femina ; 48(3): 173-176, mar. 31 2020. ilus
Article in Portuguese | LILACS | ID: biblio-1095700

ABSTRACT

Apesar da melhora no diagnóstico e tratamento, a gravidez ectópica ainda é a principal causa de mortalidade materna no primeiro trimestre da gravidez. Formas raras podem apresentar um desafio diagnóstico e, sem um diagnóstico adequado, a incidência de complicações e a mortalidade materna estão relacionadas a aumento de seus índices. Os termos "gravidez cornual" e "gravidez intersticial" têm sido utilizados de forma inconsistente na literatura, sendo frequentemente usados como sinônimos do termo "gravidez angular". Uma distinção estrita entre essas entidades pode ter implicações clínicas importantes, porque o curso natural, a propedêutica e os resultados diferem entre eles. A ressonância magnética não é o padrão-ouro para o diagnóstico de gravidez ectópica, no entanto possui relevância significativa no diagnóstico de possíveis complicações decorrentes dessa afecção. Nesse contexto, esta revisão aborda a importância da ressonância magnética na distinção dos tipos de gravidez mencionados, ilustrados por meio de casos do nosso serviço.(AU)


Despite the improvement in diagnostics and treatment, ectopic pregnancies are still the main cause of maternal mortality in the first trimester of pregnancy. Rare forms may present a diagnostic challenge and without adequate diagnosis, the incidence of complications and maternal mortality is greatly increased. The terms "cornual pregnancy" and "interstitial pregnancy" have been used inconsistently in the literature, frequently been used as synonyms and even used interchangeably with the term "angular pregnancy". A strict distinction among these entities can have important clinical implications because the natural course, management and outcomes differ among them. Magnetic resonance imaging is not the gold standard for the diagnosis of ectopic pregnancy, however, it can be useful in the diagnosis of complicated presentations of such ailment. In this context, this review highlights the importance of MRI in distinguishing the aforementioned types of pregnancies, illustrated with few cases from our service.(AU)


Subject(s)
Humans , Female , Pregnancy , Pregnancy, Ectopic/diagnostic imaging , Magnetic Resonance Spectroscopy , Pregnancy, Angular/diagnostic imaging , Pregnancy, Cornual/diagnostic imaging , Pregnancy, Interstitial/diagnostic imaging
3.
Rev. chil. obstet. ginecol ; 80(1): 55-59, 2015. ilus
Article in Spanish | LILACS | ID: lil-743835

ABSTRACT

El embarazo ectópico intersticial es una entidad rara pero con una elevada tasa de mortalidad. El diagnóstico puede resultar difícil y tardío, dada la localización del embarazo en una porción intrauterina de la trompa de Falopio. La gestación puede evolucionar de manera asintomática hasta el segundo trimestre de la gestación, y debutar con una rotura uterina y shock hipovolémico por la proximidad del saco gestacional a la arteria uterina. El tratamiento suele consistir en una resección cornual por vía laparoscópica, aunque se individualizará en función de cada caso, primando ante todo la clínica de la paciente. Se expone el caso de un embarazo ectópico intersticial que debutó con rotura uterina a las 13 semanas de gestación.


Interstitial ectopic pregnancy is a rare but with a high mortality rate entity. Diagnosis can be difficult and late, given the location of the pregnancy in an intrauterine portion of the fallopian tube. Pregnancy can evolve asymptomatic until the second trimester, and debuting with uterine rupture and hypovolemic shock due to the proximity of the gestational sac to the uterine artery. Treatment usually consists of a laparoscopic cornual resection, although it will be individualized according to each case, giving priority to the patient clinic condition. The case of an interstitial ectopic pregnancy who presented with uterine rupture at 13 weeks of gestation is presented.


Subject(s)
Humans , Female , Adult , Uterine Rupture/etiology , Pregnancy, Interstitial/surgery , Pregnancy, Interstitial/diagnostic imaging , Pregnancy Trimester, First , Shock/etiology , Ultrasonography , Laparoscopy , Stillbirth , Abdomen, Acute/etiology
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